High-Dose Psilocybin: Expanding the Research
Scientific studies increasingly support what many already intuitively feel: that a safely held, high-dose psilocybin journey can unlock deep healing, release, and reconnection.
We honour these experiences not as quick fixes, but as invitations, into a wider awareness of self, others, and the world.
Scientific Insights Meet Inner Experience
Recent clinical trials at institutions like Johns Hopkins, Imperial College London, and NYU Langone show promising results:
- Long-term reduction in treatment-resistant depression
- Breakthroughs in anxiety, trauma, and addiction
- Improvements in emotional connection and spiritual well-being
These studies suggest psilocybin quiets the brain’s Default Mode Network (DMN), creating space for new neural pathways — and new perspectives.
“I didn’t just revisit the past — I released it. It felt like a full-body exhale I hadn’t known I was holding.” - Participant, Guided High-Dose Experience
How It Works
Brain & Body
- Psilocybin binds to serotonin (5-HT2A) receptors, shifting brain connectivity
- The DMN (associated with ego, looping thoughts) quiets down
- This often results in a felt sense of clarity, peace, or even mystical union
- Emotional memory networks are more easily accessed — supporting release
Our Approach
- Always by application only
- Includes preparation, a guided ceremonial journey, and integration support
- Held by experienced facilitators in safe, trauma-informed environments
- Individual and retreat-based formats available